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Symbol Name ID |
Kras
Kirsten rat sarcoma viral oncogene homolog MGI:96680 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hepatosplenomegaly |
Hepatomegaly |
Extrahepatic cholestasis |
Jaundice |
Neoplasm of the liver |
Hepatocellular carcinoma |
| Disease(s) Associated with KRAS | ||||||
| autoimmune lymphoproliferative syndrome type 4 | ||||||
| Lynch syndrome | ||||||
| Noonan syndrome | ||||||
| pancreatic cancer |
| Mouse Phenotypes | liver/biliary system phenotype |
increased hepatocyte apoptosis |
enlarged liver |
abnormal hepatobiliary system morphology |
small liver |
liver hypoplasia |
pale liver |
increased cholangiocarcinoma incidence |
increased liver tumor incidence |
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| Availability | Mouse Genotype | |||||||||
| Krastm1Mok/Krastm1Mok | * | |||||||||
| Krastm1Tyj/Krastm1Tyj | ||||||||||
| Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Krastm4Tyj/Kras+ Meox2tm1(cre)Sor/Meox2+ (conditional) |
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| Krastm4Tyj/Kras+ Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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